Comprehensive guide
The 34 symptoms of perimenopause most doctors miss.
Comprehensive symptom map, grouped by body system, with research citations on each.
12 min read · Last reviewed May 2026
SymptomsPerimenopause
Vasomotor
Hot flashes, decoded.
KNDy neurons, the thermoneutral zone, and what fezolinetant changes about treatment options.
9 min read
SymptomsHormones
Sleep
Why insomnia hits hardest at 3 AM.
Estradiol, cortisol, GABA, and the evidence on CBT-I, MHT, and the supplements women try first.
10 min read
SleepHormones
Cognitive
The brain fog survival guide.
What changes, what doesn't, and which interventions actually have RCT evidence in midlife women.
9 min read
Brain & moodPerimenopause
Urogenital
GSM: vaginal and urinary health after 40.
Why 50–70% of postmenopausal women have GSM and most cases go untreated. The evidence on vaginal estrogen, DHEA, lasers, and lubricants.
8 min read
Sexual healthPostmenopause
HRT
HRT vs. bioidentical hormones: what the evidence actually says.
The 2002 WHI study, the 2022 NAMS update, and where the field stands now.
11 min read
Hormones & HRT
Peptides
Peptides for menopause: what the research shows.
CJC-1295, BPC-157, Tesamorelin, PT-141. Where the evidence is real, where it isn't.
10 min read
PeptidesHormones
Bone health
Bone density after menopause: beyond calcium.
SWAN bone substudy data, the LIFTMOR resistance training trial, and how bisphosphonates compare to denosumab and romosozumab.
10 min read
Bone healthPostmenopause
Supplements
The menopause supplement guide.
Black cohosh, red clover, soy, maca, vitamin D, magnesium, omega-3, ashwagandha, DIM. Each graded against the literature.
11 min read
Supplements